Enzymes are always a favorite of mine. There are just so many easy, cool labs that you can do with the kids that are very inquiry based. However, before you get to those, you need to make sure that the students understand the basics. This is where the lesson here comes in. This lesson will take students through everything they need to know about enzymes in order to apply their knowledge later in lab activities. This can be used synchronously or asynchronously. It is ready to go for students as does not need any additional guidance from you. This is formatted as an interactive digital notebook that they can save and reference later. Just give it to the students and have them complete it and turn it in to you for correction or have a class discussion about it and have them correct their own errors! Make sure to scroll to the bottom for a video preview! Here is the breakdown of the lesson: Title Slide Slide 1: What are enzymes? Students are shown the parts of an enzyme reaction in an image and introduced to substrates, products and the active site. Slide 2: Substrates are specific- Students drag the substrate that matches the correct enzyme. This shows them that only certain types of substrates match each enzyme. Here is a good place to discuss enzyme specificity. Slide 3: Active site- Students are asked to label the enzyme, substrate, product and active site in the image. The definition of the active site is discussed. Slide 4: Lock and Key Model- Students are asked to compare an enzyme and a substrate to a lock and a key Slide 5: Enzyme nomenclature- Students are introduced to the idea that enzyme names end in -ase. Students are given a paragraph and must circle the names of the enzymes. Slide 6: Enzymes can denature- Students are introduced to the idea of denaturation. Students are asked to drag the substrate to the enzyme which has been denatured. The substrate will not fit. This shows that the enzyme cannot do its job. Students are asked to write why that is. Slide 7-9: Lactose Intolerance Case Study- The intestines of 2 patients are shown. Students are asked to drag the substrates to the enzyme in patient #1, the lactose tolerant patient. There is a substrate for every enzyme, and thus the person can digest the lactose. With patient #2, there are not enough enzymes to digest the substrates, so some of the substrates stay in the intestines, causing problems. This person is lactose intolerant. Students are then asked to determine which person is lactose tolerant and which is lactose intolerant. They are then asked how lactose free milk would help someone with lactose intolerance. Slide 10-11:Enzymes and Activation Energy- Students are introduced to the definition of AE. Students are then shown how AE can be compared to pushing a boulder over a hill. The hill without the enzyme is larger. Students record how much energy was used to get the boulder over the hill without the enzyme. On the next slide, students are asked to now look at the size of the hill with an enzyme and record the amount of energy needed. They then compare this analogy to the rate of a chemical reaction. Slide 12: AE graphs- Students use the knowledge gained in the previous slides to label which part of the graph represents AE with an enzyme and without an enzyme. They they explain their reasoning. Slide 13: Rate of Reaction- Students are introduced to the idea that adding more enzyme to a reaction can speed it up. Students drag the enzymes onto the slide to substrates to speed up the reaction. Slide 14: Catalyst- In this slide, an enzyme is related to a catalyst. Slide 15: Specific pH- Students are shown a pH scale and told that enzymes work best at specific temperatures and pH levels. Students are asked at which pH a stomach enzyme would work best, and at which pH a mouth enzyme would work best. They use the scale to answer the questions. Slide 16: Exit Ticket- Students are asked in 20 words, to describe WHY enzymes are important to the body and how they work. This lesson would also go well with our Digestive System Lesson (for distance learning) Interested in this lesson? Check out our TpT store.
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